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Home Q & A Board Biology-Related Homework Help Genetics and Developmental Biology
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EvaRL EvaRL
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9 years ago
how can substitution errors happen during replication? Is it possible for two purine or pyrimidine bases to bond to each other? So how can the enzyme put a T instead of a C, for example, if it won't bind to the G on the other side?
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#1
Educator
9 years ago
Yes, it can. In fact, a lot of mistakes are made, but then corrected by other enzymes designed to correct mistakes. The incorrect base won't allow for correct annealing to take place.

I forgot which enzyme it is, but one major enzyme is designed to both add and correct simultaneously.
EvaRL Author
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#2
9 years ago
I'm sorry; I don't understand your answer. You're saying that it is possible for a C to bind to a T, etc?
wrote...
#3
Educator
9 years ago
Quote from: EvaRL (9 years ago)
I'm sorry; I don't understand your answer. You're saying that it is possible for a C to bind to a T, etc?

No. It's not possible.

Quote
The incorrect base won't allow for correct annealing to take place.
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