Top Posters
Since Sunday
5
a
5
k
5
c
5
B
5
l
5
C
4
s
4
a
4
t
4
i
4
r
4
Home Q & A Board Biology-Related Homework Help Cell Biology
New Topic  
adhungan adhungan
wrote...
Go to Answer
Posts: 61
Rep: 21 0
9 years ago
Describe a way that scientists can use to determine if a protein is located on the exoplasmic face of the cell membrane. 

Please helppp !!
Read 508 times
4 Replies
Replies
wrote...
#1
Educator
9 years ago
Start with this definitions:

Exoplasmic face

You're asking, what characteristics would a peptide have in order to be in the exoplasmic face - I'm not sure Face with Stuck-out Tongue

I did find this information that might help --

Quote
Many such proteins contain a single membrane-spanning segment: a sequence of 20 – 25 hydrophobic amino acids that forms a transmembrane α helix, anchoring the protein in the phospholipid bilayer. Most of these single-pass transmembrane proteins have their hydrophilic N-terminal segment on the exoplasmic face and their hydrophilic C-terminal segment on the cytosolic face; other single-pass proteins have the reverse orientation. Many plasma-membrane proteins have multiple membrane-spanning α-helical segments. Such multi- pass transmembrane proteins include the glucose transporter GLUT1 and numerous G protein – linked cell-surface receptors. Still other membrane proteins, which lack a hydrophobic membrane-spanning segment, are linked to a glycosylphosphatidylinositol (GPI) anchor that is embedded in the phospholipid bilayer.
Source  http://www.ncbi.nlm.nih.gov/books/NBK21731/
adhungan Author
wrote...
#2
9 years ago
Quote from: bio_man (9 years ago)
Start with this definitions:

Exoplasmic face

You're asking, what characteristics would a peptide have in order to be in the exoplasmic face - I'm not sure Face with Stuck-out Tongue

I did find this information that might help --


I need the method that scientist use to find where the proteins are located. As in the explasmic face of cell membrane.

Quote
Many such proteins contain a single membrane-spanning segment: a sequence of 20 – 25 hydrophobic amino acids that forms a transmembrane α helix, anchoring the protein in the phospholipid bilayer. Most of these single-pass transmembrane proteins have their hydrophilic N-terminal segment on the exoplasmic face and their hydrophilic C-terminal segment on the cytosolic face; other single-pass proteins have the reverse orientation. Many plasma-membrane proteins have multiple membrane-spanning α-helical segments. Such multi- pass transmembrane proteins include the glucose transporter GLUT1 and numerous G protein – linked cell-surface receptors. Still other membrane proteins, which lack a hydrophobic membrane-spanning segment, are linked to a glycosylphosphatidylinositol (GPI) anchor that is embedded in the phospholipid bilayer.
wrote...
#3
Educator
9 years ago
Neutral Face
Answer accepted by topic starter
DrDolittleDrDolittle
wrote...
#4
Posts: 9
Rep: 31 0
9 years ago Edited: 9 years ago, DrDolittle
Sign in or Sign up in seconds to unlock everything for free
This verified answer contains over 170 words.
1

Related Topics
New Topic      
Quick Reply
Explore
Post your homework questions and get free online help from our incredible volunteers
  1291 People Browsing
Start New Topic Take the Tour CoursesNew Study Tools Topics Trending Browse by Textbook
Live Chat
Related Images
  
 271
  
 123
  
 54
Your Opinion
Where do you get your textbooks?
Votes: 372
Previous poll results: What's your favorite funny biology word?