What factors contribute to the short (approximately 120-day) life span of an er

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What factors contribute to the short (approximately 120-day) life span of an er

What factors contribute to the short (approximately 120-day) life span of an erythrocyte?

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duddy

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11 years ago

As they differentiate and mature, erythrocytes lose most of their organelles, thereby forfeiting any mechanism for repair. Also, erythrocytes are exposed to severe stresses caused by making a complete circulatory circuit approximately every 30 seconds, participating in rouleaux, squeezing through small capillaries, and in general suffering much wear and tear from traveling 700 miles in 120 days. After this time they are phagocytized.

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