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Home Q & A Board Biology-Related Homework Help Cell Biology
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davethenuge davethenuge
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11 years ago
This is kind of hard to explain, but I know if there was a insertion, the pre-mRNA would be longer. But if it was in an intron and therefore got spliced out, would the mRNA be normal? Or still messed up as well?

Please help!
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#1
11 years ago
You got that right.  as long the mutation doesn't produce any cryptic splice sites, any insertion would not cause a shift in the reading frame.  The sequence is not going to be in the mature mRNA at all, it will be spliced out.
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