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Down regulation blood glucose transporters

jeeyoung

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8 years ago

Down regulation blood glucose transporters

diabetes mellitus patients often have down-regulated blood glucose transporters in the blood brain barrier. why? Due to this, what effect could insulin therapy have on this patient?

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bio_man

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8 years ago

Insulin makes sugar more "permeable" to the cell's membrane by increasing binding to insulin receptors on target cells, in this case the brain, and opening the glucose channels.

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