× Didn't find what you were looking for? Ask a question

Recent Posts • Latest Topics • Unanswered Questions

Top Posters

Since Sunday

5

a

5

k

5

c

5

B

5

l

5

C

4

s

4

a

4

t

4

i

4

r

4

What is the difference between a loss of function mutation and leaky mutation?

Moso13

wrote...

Posts: 21

Rep:

6 years ago

What is the difference between a loss of function mutation and leaky mutation?

Is a null mutation the same thing as a loss of function mutation?

Read 126 times

1 Reply

Related Topics

Solved An example of a gain of function missense mutation is a mutation of the TP53 gen
Solved Cystic fibrosis is caused by a recessive loss-of-function mutation that encodes a protein called the
Solved Cystic fibrosis in humans is caused by a recessive loss-of-function mutation in a locus on chromosom
Solved In order for a mutation to be passed on to offspring, the mutation must:
Solved Since the mutation produced a specific wing trait that was passed on, the mutation must have ...
Solved Consider a gene with a particular function. Mutation X and mutation Y each cause defects in the ...
Please identify the nonsense mutation in the following figure.
What is the difference between a forward and reverse mutation?

Show More

Replies

bio_man

wrote...

#1

Educator

6 years ago

Null vs loss of function. Short answer, they are different.

Loss-of-function mutations, also called inactivating mutations, result in the gene product having less or no function (being partially or wholly inactivated). When the allele has a complete loss of function (null allele), it is often called an amorph or amorphic mutation.

Less-severe mutations are called “leaky” mutations because some normal function still “leaks through” into the phenotype.

Explore

Post your homework questions and get free online help from our incredible volunteers

1230 People Browsing

Start New Topic Take the Tour CoursesNew Study Tools Topics Trending Browse by Textbook

Live Chat

AJAX Chat © blueimp.net Integrated with SMF

Related Images

186

1218

129

Your Opinion

Previous poll results: Should Ph.D.'s be addressed as doctors?

Bonobos, Chimpanzees, and the 98% DNA Link

The Toxic Skin and Fungi Defense

Strange Ingredients Lurking in Doritos Chips

It's sore throat season, why does my mucus have red spots?

Courses by Biology Forums

Ready to ask a question on Biology Forums? Try it out

Join Our Community

Biology Forums - Study Force is a free online homework help service catered towards college and high school students. Get homework help and answers to your toughest questions in biology, chemistry, physics, mathematics, engineering, accounting, business, humanities, and more. Master your assignments quickly with thousands of step-by-step solutions to countless textbook questions asked and answered by our members. If we don't have your question, don't worry. You can ask any homework question and get expert homework help in as little as two hours.

Our extensive online study community is made up of college and high school students, teachers, professors, parents and subject enthusiasts who contribute to our vast collection of study resources: textbook solutions, study guides, practice tests, practice problems, lecture notes, equation sheets and more. With our help, your homework will never be the same!

Join for free today

How is Biology Forums - Study Force different than tutoring?

Home Search Q & A Board Gallery Resource Library Blog Dictionary Chat	Quick Links Start a Topic Latest Topics Unanswered Questions Courses Study Tools Browse by Textbook	Social Facebook YouTube Community Stats Who's Online Trending Staff	Help About Us Take the Tour Study Tips Posting Guidelines Terms and Policies Contact Us
Biology Forums - Study Force © 2010-2024 \| Powered by SMF \| SMF © 2015, Simple Machines \| Sitemap Biology-Forums.com is not affiliated with any publisher. Book covers, title and author names appear for reference only.