(Solved) Genetics question?help?

Ilovehim

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11 years ago

Hemophilia is a sex-linked trait. If a woman with hemophilia marries a man who does not have hemophilia, what is the probability they will have a son with hemophilia? A daughter?

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lemonjello

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11 years ago

just learned this! anyway, hemophilia is a recessive gene, and for it to be passed down and actually show up both parent have to have this kind of homozygous recessive gene or heterozygous recessive gene. at least that's how I interpreted what my teacher was saying. hopefully this helps!

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lema

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11 years ago

The genotypes of the parents are:
Mother: X' X'
Father: X Y
(assume X - normal X chromosome, X' - diseased X chromosome that results in haemophilia if homozygous/ hemizygous)
Any son will get his X chromosome from the mother, so the probability that he will suffer from haemophilia is 100%. A daughter gets one X from each parent. The father's X chr. is normal and hence, although any daughter will be a carrier of the disease, the probability that she will suffer from it is 0%.
This is only theoretical, as it is extremely unlikely that any woman with haemophilia can survive long enough to have children.

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