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Familial Mediterranean Fever (FMF) results in short but reoccurring episodes of fever as well as pain in the chest, joints, and abdomen. The disease occurs most frequently in individuals of Mediterranean descent. The gene responsible for FMF was discovered on chromosome 16 in 1997.
The following pedigree shows the occurrence of this disorder in one family. Provide the phenotypes and genotypes of all individuals in the pedigree. Of whose genotypes can you not be sure? Enter phenotypes as "affected" or "normal". Enter genotypes as RR, Rr, rr, or R_ for unknown.
How is FMF inherited? Enter your answer as "autosomal", "X-linked" or "Y-linked".
I - 1 phenotype is Answer and genotype is Answer.
I - 2 phenotype is Answer and genotype is Answer.
II - 1 phenotype is Answer and genotype is Answer.
II - 2 phenotype is Answer and genotype is Answer.
II - 3 phenotype is Answer and genotype is Answer.
II - 4 phenotype is Answer and genotype is Answer.
III - 1 phenotype is Answer and genotype is Answer.
III - 2 phenotype is Answer and genotype is Answer.
III - 3 phenotype is Answer and genotype is Answer.
III - 4 phenotype is Answer and genotype is Answer.
IV - 1 phenotype is Answer and genotype is Answer.
IV - 2 phenotype is Answer and genotype is Answer.
IV - 3 phenotype is Answer and genotype is Answer.
How is FMF inherited? Answer
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Duchenne muscular dystrophy is an X-linked recessive trait. The following pedigree shows the occurrence of this disorder in an extended family.
Provide the phenotypes and genotypes of all individuals in the pedigree.
Enter phenotypes as affected or normal.
When entering the genotypes, use one of the following: XDXd, XdXd, XDXD, XdY, or XDY; where XD represents the dominant allele and Xd represents the recessive allele.
I - 1 phenotype is Answer and genotype is Answer.
I - 2 phenotype is Answer and genotype is Answer.
II - 1 phenotype is Answer and genotype is Answer.
II - 2 phenotype is Answer and genotype is Answer.
II - 3 phenotype is Answer and genotype is Answer.
II - 4 phenotype is Answer and genotype is Answer.
III - 1 phenotype is Answer and genotype is Answer.
III - 2 phenotype is Answer and genotype is Answer.
III - 3 phenotype is Answer and genotype is Answer.
III - 4 phenotype is Answer and genotype is Answer.
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This pedigree traces tongue rolling in a family. Black circles and squares represent the ability to roll the tongue.
The ability to roll your tongue is controlled by a dominant allele; people with the recessive allele cannot roll their tongues. Identify the phenotypes and genotypes of all the people shown in this pedigree. Enter phenotypes as roll or not. Enter gentoypes as RR, Rr, or rr.
I - 1 phenotype is Answer and genotype is Answer.
I - 2 phenotype is Answer and genotype is Answer.
II - 1 phenotype is Answer and genotype is Answer.
II - 2 phenotype is Answer and genotype is Answer.
II - 3 phenotype is Answer and genotype is Answer.
II - 4 phenotype is Answer and genotype is Answer.
III - 1 phenotype is Answer and genotype is Answer.
III - 2 phenotype is Answer and genotype is Answer.
III - 3 phenotype is Answer and genotype is Answer.
III - 4 phenotype is Answer and genotype is Answer.
III - 5 phenotype is Answer and genotype is Answer.
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