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Linked genes are 50 M.U.'s apart. You will not recover >50% recombinants. Why?
Linked genes are 50 M.U.'s apart. You will not recover >50% recombinants. Why?
Here is the question:

If two genes are linked on a chromosome and over 50 map units apart, in theory you will not recover more than 50% recombinants, which is the same as independent assortment (genes on two different chromosomes). Using diagrams, show why this is so.

Thank You
Genetics and Developmental Biology   thinkgr33n   1506   Asked 10 years ago
Indicate which allelic combinations each individual has
Indicate which allelic combinations each individual has
I know the answer already because the key was given but I don't know why the answer is what it is. I thought the progeny in generation III all had parental allelic combinations but that's not so. Why is that?

The answer is PPPRP but I thought it was PPPPP
Genetics and Developmental Biology   saneclarity   346   Asked 10 years ago
Heterozygous inversion test cross
Heterozygous inversion test cross
Below is a map of the Drosophila melanogaster X chromosome, giving the distances between adjacent genes in centiMorgans.  
 
sn-----------------lz------------v----------wy-----------m-------s------g
   6.7            5.3         3.2          4.5        2.3    1.
Genetics and Developmental Biology   wyki   962   Asked 10 years ago
Genetics - Gene Mapping
Genetics - Gene Mapping
In Drosophila, four genes on the X chromosome are sites of recessive mutations causing yellow body (y), white eyes (w), miniature bristle (m), and small wings (sm). In a test cross of F1 triple heterozygous female (obtained by crossing two pure-breeding P1 stocks) with (m y w)/Y males, seven classes of progeny were recovered and counted among 400 F2 flies.

yellow white      1
Genetics and Developmental Biology   mfyda10   858   Asked 10 years ago
What is functional sequence evolution?
What is functional sequence evolution?
What is functional sequence evolution?
Genetics and Developmental Biology   ehd123   222   Asked 10 years ago
need help with confusing genetics problem
need help with confusing genetics problem
I can't figure out how to do the punnet square for any of this or what it all means? Can anyone please explain how to understand the solution? Looks like a bunch of letters and numbers to me.

Red-green color-blindness is an X-linked recessive trait in humans. Polydactyly (extra fingers and toes) is an autosomal dominant trait. Martha has normal fingers and toe
Genetics and Developmental Biology   centimetergrove   473   Asked 10 years ago
EMERGENCY: Need help with UMUC Lab # 5 Genetic Inheritance
EMERGENCY: Need help with UMUC Lab # 5 Genetic Inheritance
Lab # 5
Genetic Inheritance

Section A: Patterns of Inheritance

Background Information
In the 19th century, a monk named Gregor Mendel conducted a series of experiments to determine how ‘traits’ or features of pea plants were passed on from generation to generation.  He carefully studied seven traits of successive generations of pea plants to disc
Genetics and Developmental Biology   Dave11   1372   Asked 10 years ago
Interpreting Cladograms
Interpreting Cladograms
Indicate whether each of these is plesiomorphic (ancestral) or apomorphic (derived) in the great ape lineage, using the phylogeny below. Great apes include orangutan, gorilla, chimp, and human.

Genetics and Developmental Biology   beardy   440   Asked 10 years ago
Paraphyletic groups
Paraphyletic groups
Which of these are paraphyletic groups?

Reptiles
Trees
Apes
Birds
Plants
Whales
Fish
Seaweed
Dinosaurs
Prokaryotes
Eukaryotes
Invertebrates
Humans
Chimps
Warm-blooded Animals

Genetics and Developmental Biology   beardy   408   Asked 10 years ago
Flawed phylogeny reasoning
Flawed phylogeny reasoning
A scientist wanted to compare the evolution of the families Balaenopteridae (the rorqual baleen whales) and Delphinidae (the dolphins). Balenopteridae consist of about 11 species while Delphidae consist of about 41 species. The scientist proposes the hypothesis that evolution has occurred more rapidly in Delphinidae due to their active, predatory lifestyle, while the baleen whales,
Genetics and Developmental Biology   beardy   2296   Asked 10 years ago
need help please
need help please
1- Baur and Shull crossed broad-leaved females of the plant species Lychnis alba to narrow-leaved males and obtained an F1 consisting of males and females that were all broad leaved, but the F2 were of two kinds, broad-leaved and narrow-leaved.  Explain the type of sex determination system that exists in Lychnias alba.  SHOW YOUR WORK .
a- Type of system?
b- what
Genetics and Developmental Biology   rony   638   Asked 10 years ago
Fusion of two mutant haploid cells to produce a cell that grows on minimal media
Fusion of two mutant haploid cells to produce a cell that grows on minimal media
I have attached the question(#25).Can someone please explain this conceptually.I know it has to do with complementation.
Genetics and Developmental Biology   s2kmanny   472   Asked 10 years ago
cdna vs genomic library
cdna vs genomic library
The first genomic library ever made was for the beta-globin gene taken from human genomic dna of the reticulocytes.
the library was done by using a partial digestion of the genome via restriction enzymes.
[ a partial digest is done by not allowing the reaction to go to completion achieved by limiting incubation time]
the fragments were then transferred to vectors of
Genetics and Developmental Biology   ehd123   957   Asked 10 years ago
cDNA vs genomic libraries
cDNA vs genomic libraries
The first genomic library ever made was for the beta-globin gene taken from human genomic dna of the reticulocytes.
the library was done by using a partial digestion of the genome via restriction enzymes.
[ a partial digest is done by not allowing the reaction to go to completion achieved by limiting incubation time]
the fragments were then transferred to vectors of
Genetics and Developmental Biology   ehd123   654   Asked 10 years ago
Genetic Map & Interference
Genetic Map & Interference
Two theoretical genetic strains of a virus (a − b − c − and a + b + c +) were used to simultaneously infect a culture of host bacteria. Of 10,000 plaques scored, the following genotypes were observed. Determine the genetic map of these three genes on the viral chromosome. Decide whether interference was positive or negative.   
a+b+c- 41000
Genetics and Developmental Biology   crw09e   2580   Asked 10 years ago
Linkage Relationship
Linkage Relationship
In a transformation experiment, donor DNA was obtained from a prototroph bacterial strain (a + b + c +), and the recipient was a triple auxotroph (a − b − c −). What general conclusions can you draw about the linkage relationships among the three genes from the following transformant classes that were recovered?
a+ b- c- 180
a- b
Genetics and Developmental Biology   crw09e   2492   Asked 10 years ago
One strand of a fragment of duplex DNA has the sequence 5'-A-T-C...
One strand of a fragment of duplex DNA has the sequence 5'-A-T-C...
Hey everybody have a few questions.

Part E what enzyme catalyzes the reaction in part D

Part F what type of bond joins one strand of DNA duplex to the other strand.

Part H
What term is used to describe the pattern of base pairing between one DNA strand and its partner in a duplex?

Part I
What term is used to describe the polarit
Genetics and Developmental Biology   fodog414   10538   Asked 10 years ago
One result of X-linkage is a crisscross pattern of inheritance in which
One result of X-linkage is a crisscross pattern of inheritance in which
One result of X-linkage is a crisscross pattern of inheritance in which sons express recessive genes of their fathers and daughters express recessive genes of their mothers.

a.   True
b.   False

Post Merge: 10 years ago

False, One result of X-linkage is a crisscross pattern of inheritance in which sons express recessi
Genetics and Developmental Biology   Bella0415   2460   Asked 10 years ago
Creation of CFTR Knockout Mice by Injection of KO ES Cells into a Blastocyst
Creation of CFTR Knockout Mice by Injection of KO ES Cells into a Blastocyst
I'm really having a tough time with this KO mouse concept. If anyone could explain what is going on in each step, this would really help me.
Genetics and Developmental Biology   willuhelp   423   Asked 10 years ago
Creation of CFTR Knockout Embryonic Stem Cells by Positive-Negative Selection
Creation of CFTR Knockout Embryonic Stem Cells by Positive-Negative Selection
I am having trouble understanding what is going on here. What I got thus far is that the more preferred fate is Homologous recombination (targeted approach). Next, you basically plate the ES cells that are both neomycin & ganciclovir resistant (homologous recombination). I basically do not know if I am on the right track. Any feedback of any sort will help.
Genetics and Developmental Biology   willuhelp   369   Asked 10 years ago
translate this into protein using the genetic code table.
translate this into protein using the genetic code table.
Below is a sequence of double stranded DNA from a bacterium.  Based on what you know about bacterial transcription and translation, put an “X” next to the strand that is most likely to be the template strand for transcription and give a brief answer for your choice (5-10 words).  Then,
   •   clearly underline the likely coding sequence
   •   transcribe it into mRNA
Genetics and Developmental Biology   asjd11   612   Asked 10 years ago
Calculate relatedness
Calculate relatedness
Is it possible to calculate the relatedness between family members(consanguineous) if you have the genotypes at all positions on te chromosomes.

Let me try to explain what I'm doing now:

A person can have 3 types of genotypes for example AA, BB and AB. If you combine 2 persons you will get a total of 9 different types of combinations.(AAAA,BBBB,ABAB,AAAB,B
Genetics and Developmental Biology   Thuur   685   Asked 10 years ago
Tetrad analysis and Perkins formula
Tetrad analysis and Perkins formula
Hi I'm currently taking genetics at my school and the section on haploid genetics (i.e. Neurospora) has me dazed. Can anyone explain clearly how tetrad analyis works, what PD,NPD,T all represent and how they all come together in the so-called Perkin's formula? (the derivation) Thanks!
Genetics and Developmental Biology   dreamh317   2584   Asked 11 years ago
mutation-selection balance
mutation-selection balance
I'm having problems figuring out the logic behind two formulas related to the Hardy-Weinberg equation. Here are two relevant excerpts from my textbook, Medical Gentics by Jorde, Carey and Bamshad:

Quote
Consider, for example, a dominant disease that results in death before the person can reproduce. This is
termed a genetic lethal mutation because, even though t
Genetics and Developmental Biology   Tomato   577   Asked 11 years ago
Dual Luciferase Reporter Gene Assays
Dual Luciferase Reporter Gene Assays
The accuracy of reporter assays can be improved by utilizing a dual reporter system. One of the reporter genes is correlated with the promoter of interest and is used to assess the effects of specific experimental conditions, while the second reporter is used as a control and serves as a baseline response. The Super Light™ Dual- Luciferase Reporter Assay allows for the sequential me
Genetics and Developmental Biology   MarkHolland   493   Asked 11 years ago
A mutation in which gene could be responsible for this biosynthetic auxotroph
A mutation in which gene could be responsible for this biosynthetic auxotroph
One of my mutants [EMS-mutagenized, ampicillin enriched, 99.9% killing] grew only [! only] on a plate containing arginine, aspartate, proline, glutamic acid, inositol, and ornithine. I've spent hours trying to find out where the mutation might be [i have found out how all the amino acids on the plate are related using ecocyc], but i can't pinpoint an intermediate that woul
Genetics and Developmental Biology   KLOB   743   Asked 11 years ago
restriction mapping
restriction mapping
here is the data, i figured out that there is three overlaps in the Hind3 and EcoR1 at the 21200 and the 350 mark and the 2700 mark. that means it was cut twice? but after that i dont know where to go.

EcoR1                                         Both      &
Genetics and Developmental Biology   julle12345678   634   Asked 11 years ago
how to analyse PCR
how to analyse PCR
The question asks  to calculate the tandem repeats in the D1S80 allele. i plotted the graph but im not sure what to do from there.
next question asks to be figure outhow many diffferent classes of homozygous and heterozygous exist?
any help will be greatly appreciated
Post Merge: 11 years ago

anyone?
Genetics and Developmental Biology   julle12345678   544   Asked 11 years ago
help analyzing this paragraph from journal article
help analyzing this paragraph from journal article
In this journal "Evolutionary History and Adaptation from High-Coverage Whole-Genome Sequences of Diverse African Hunter Gatherers" by Lachance et. al , I am having a hard time trying to figure out what this certain section is saying.

Under "Evidence of Archaic Introgression" - We didn't find strong evidence that introgressed regions were clustere
Genetics and Developmental Biology   omgwtfitsp   640   Asked 11 years ago
Transmission Ratio Distortion
Transmission Ratio Distortion
Transmission Ratio Distortion is the inheritance of genes in a non-mendelian ratio.
Also known as meiotic drive..

Can anyone give me some of the general characteristics of a TRD system?
Thank you in advance!
Genetics and Developmental Biology   crmilano   485   Asked 11 years ago
I have no clue where to start.
I have no clue where to start.
Theodore was a highly inbred handsome rat with a very long tail (30 cm), while his equally
inbred yet striking mate, Spacey, had a petite tail (6 cm). When Theodor and Spacey had their
first litter, all had 18-cm tails. When the babies grew up and interbred, they produced 256 F2’s
with tails ranging in size from 6 cm to 30 cm in the following intervals: 6, 10, 14, 18,
Genetics and Developmental Biology   BioMajor17   1448   Asked 11 years ago
why is it easier to study products of meiosis in fungi than in plants andanimals
why is it easier to study products of meiosis in fungi than in plants andanimals
why is it far easier to study the products of meiosis from a single meiocyte in fungi, as compared to plants or animals?
Genetics and Developmental Biology   moe6141   743   Asked 11 years ago
IS small sex organ a recessive or dominant trait in Genetics?
IS small sex organ a recessive or dominant trait in Genetics?
This is for my SCIENCE HOMEWORK. My genetics teacher wanted us to go out and find the answer. HELP?
Genetics and Developmental Biology   Sm4450   4440   Asked 11 years ago
Anyone have a download link for the solutions man.
Anyone have a download link for the solutions man.
Hi looking for a download link to the solutions book for Introduction to genetic analysis tenth edition
Genetics and Developmental Biology   Jthomas32090   3257   Asked 11 years ago
A few doubts regarding Heart (Atrial) Embryology...
A few doubts regarding Heart (Atrial) Embryology...
HI GUYS  Waving Hand Sign

1. What is the developmental significance of both the Atrial appendages, i.e. what is the reason for their presence?  What I mean is, is it just to increase its volume as man has more oxygen and nutritional requirements all of a sudden in the developmental tree or what?

2. Why does septum spurium develop at all? It anyways is incorporat
Genetics and Developmental Biology   the13thhokage   1297   Asked 12 years ago
The Recent Resurgence Of Long Supressed Evidence That Glockomeyoma Is Palamenic
The Recent Resurgence Of Long Supressed Evidence That Glockomeyoma Is Palamenic
Genetics and Developmental Biology   NeoshadowXC   1620   Asked 12 years ago
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