Compare and contrast the holes-in-therepertoire model and the determinant-selection model of immune ...

kay20213

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6 years ago

Compare and contrast the holes-in-therepertoire model and the determinant-selection model of immune responsiveness.

What will be an ideal response

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joshbauer

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6 years ago

In the determinant-selection model, differences in responsiveness are explained by the ability or inability of MHC to bind peptide. In the holes-in-the repertoire model, differences in responsiveness are explained by the presence or absence of specific T cells. T cells that respond to certain peptides may be deleted during selection on certain MHC backgrounds.

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kay20213 Author

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6 years ago

So smart

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