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barry barry
wrote...
Posts: 11630
12 years ago
Exactly why, in dideoxy DNA sequencing, do dideoxynucleotides halt the replication process?
Source  iGenetics: A Molecular Approach, 3e (Russell/Bose)
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wrote...
Staff Member
12 years ago
Dideoxynucleotides are missing the 3' hydroxyl group necessary for linkage with the 5' phosphate group of new nucleotides by DNA polymerase.
- Master of Science in Biology
- Bachelor of Science
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