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Rizwan030 Rizwan030
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7 years ago
Hi, 
I have a question that.  When a donor blood group ' B' blood.,  FOR EXAMPLE,  transfuse a blood group ' AB'  recpient,  then donor rbcs and antibodies are diluted in recpient  serum.  Both rbcs and antibodies are low quantity  and both are diluted.  Then why we only importance to red cells? Whey donor antibody  not create big problem to recpient ?
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wrote...
7 years ago
 It is because transfusion is done where whole blood is not transfused, just the individual components such as red blood cells, plasma, or platelets. If whole blood is collected, it is then centrifuged to separate the components, and stored that way.

The antibodies are found in the plasma portion of blood, so when type A red cells are transfused, there is hardly any plasma present because it has been removed, so there is not a reaction. If you were to transfuse type A plasma to an AB individual, it would cause a reaction, because the anti-B would attach to the red cells and lyse them (break them apart).
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