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steve_with_45 steve_with_45
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12 years ago
. Mrs. James appeared at the clinic complaining of extreme nervousness and sweating, saying that she could feel and hear her heart thumping when she tried to sleep at night. Laboratory testing revealed hyperglycemia and increased basal metabolic rate. Although she also proved to have high blood pressure, tests of thyroid function were normal. What is your diagnosis? What treatment should be used?
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wrote...
Staff Member
12 years ago
It seems to be phenochromocytoma. Phenochromocytoma produces catecholamines which causes anxiety, sweating, palpitation, hyperglycemia, high metabolic rate, high blood pressure. Surgical resection is the standard curative modality.
- Master of Science in Biology
- Bachelor of Science
wrote...
12 years ago
Hi I have a brother that is a diabetic so sounds like:

Hypersecretion of insulin - hyperinsulinism

    A tumor of the islet beta cells will cause an overproduction of insulin.  This will produce a pronounced hypoglycemia.  There is a very low incidence of this condition.

Symptoms:

1.  Anxiety and sweating.
2.  Body tremors
3.  Elevated body temperature
4.  Disorientation
4.  The patient can go into Insulin shock due to brain hypoglycemia. 

Or maybe:

Hypersecretion of adrenal steroids - Cushing's syndrome

Chief causes of Cushing's syndrome:

1.  Hypersecretion of ACTH - Pituitary Cushing's syndrome is responsible for 60 to 70% of these cases.  This condition is brought on by a pituitary adenoma.

2.  Hypersecretion of adrenal steroids due to an adenoma of the adrenal cortex (20% of the cases) produces low levels of ACTH by negative feedback.  This is called adrenal Cushing's syndrome.

3.  Hypersecretion of ACTH by a non-endocrine cancer, e.g., lung carcinoma.  This is called paraneoplastic Cushing's syndrome and is responsible for 10 to 15% of the cases.

4.  Iatrogenic Cushing's syndrome is due to the long term use of glucocorticoids to control inflammation and edema or autoimmune diseases like rheumatoid arthritis.

Symptoms:

1.  Hyperglycemia due to enhanced gluconeogenesis.
2.  Catabolism of body protein producing poor wound healing, easy bruising and muscular weakness.
3.  Decreased immunity.
4.  Hypernatremia leading to excessive water retention.
5.  Hyperkalcemia and high blood pressure.
6.  Shifting of fat deposits to the face ("moon face") and upper torso ("Buffalo hump").
7.  In a male child - Muscular hypertrophy ("pocket Hercules").
8.  In a female child or adult - Virilsm (bearded lady).

Just guesses, get back to us to let us know, GL
Mz
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