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lawyerflaw lawyerflaw
wrote...
14 years ago
What's the difference between DNA primase and RNA primase? And which is used in DNA replication?
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hey Author
wrote...
#1
14 years ago
hey I came across ur question through google, thought i would share some knowledge Slight Smile

okay... As the names suggest, RNA primase only works to build RNA, while DNA primase can only work to build DNA... primases generally initiate DNA replication by synthesizing short RNA primers on single-stranded DNA (ssDNA) that are then extended by the replicative DNA polymerase(s). remember that primers are required to start the new dna strand being built, they are then removed by other enzymes because rna primers include nucleotides that are not found in dna.
lawyerflaw Author
wrote...
#2
14 years ago
Quote from: hey (14 years ago)
hey I came across ur question through google, thought i would share some knowledge Slight Smile

okay... As the names suggest, RNA primase only works to build RNA, while DNA primase can only work to build DNA... primases generally initiate DNA replication by synthesizing short RNA primers on single-stranded DNA (ssDNA) that are then extended by the replicative DNA polymerase(s). remember that primers are required to start the new dna strand being built, they are then removed by other enzymes because rna primers include nucleotides that are not found in dna.


Highlighted in red.. so is that DNA primase or RNA primase?
wrote...
#3
Valued Member
14 years ago
rna primase has to do with making rna
dna primase has to do with making new dna strands

DNA primases catalyse the synthesis of the short RNA primers on single stranded (ss) DNA templates that are used by DNA polymerase to initiate the synthesis of Okazaki fragments on the lagging strand
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