Why increasing extracellular K+ causes the membrane potential to change to a less negative value. ...

jdmking18

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12 years ago

Why increasing extracellular K+ causes the membrane potential to change to a less negative value. ...

why increasing extracellular K+ causes the membrane potential to change to a less negative value. How well did the results compare with your prediction?

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duddy

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Staff Member

12 years ago

Increased extracellular potassium levels result in depolarization of the membrane potentials of cells. This depolarization opens some voltage-gated sodium channels, but not enough to generate an action potential.

"Potassium ions had the greatest effect because increased potassium (hyperkalemia) decreases the resting potential of cardiac muscle plasma membranes, thus decreasing the force of heart contraction."

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