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why is isocitrate dehydrogenase inhibited by ATP?

nursestudent

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11 years ago

why is isocitrate dehydrogenase inhibited by ATP?

Could somebody please explain why ATP and NADH inhibit isocitrate dehydrogenase? I believe that NADH may inhibit it because of negative feedback inhibition, as NADH is produced as a byproduct. However, I am completely clueless on where ATP fits into the picture??

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Michele

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11 years ago

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