× Didn't find what you were looking for? Ask a question
Top Posters
Since Sunday
5
o
5
4
m
4
b
4
x
4
a
4
l
4
t
4
S
4
m
3
s
3
New Topic  
gautam gautam
wrote...
13 years ago
Is it feasible/possible to measure the interferon tau (NOT the ISG) in blood sample of inseminated cows ?
I was searching the for " determination of interferon tau". But all searched results show "interferon tau stimulated genes". I am interested only on "interferon tau", NOT on "interferon stimulated genes". I would be grateful if someone suggests me how to determine "interferon tau" in inseminated cows (not the ISG).
Read 1526 times
2 Replies

Related Topics

Replies
wrote...
13 years ago
Hey Gautam, welcome!

Please post your question in a single category.

It will be answered shortly.
B.Sc. (Biology)
wrote...
Valued Member
Educator
13 years ago
Interferon tau is the signal from the developing embryo to the mother that she is pregnant. It is secreted by the trophoblast cells into the uterine lumen in days 13-21 of pregnancy. It decreases endometrial oxytocin receptors, which then cannot stimulate PGF-2-alpha synthesis, preventing luteolysis. It promotes uterine implantation by increasing protein synthesis in glands.

I found the following papers to aid you:

1) http://www.ncbi.nlm.nih.gov/pubmed/20554404

Measurement of interferon-tau (IFN-tau) stimulated gene expression in blood leukocytes for pregnancy diagnosis within 18-20d after insemination in dairy cattle.

2) http://www.ncbi.nlm.nih.gov/pubmed/11343838

Genetic and environmental determinants of interferon-tau secretion by in vivo- and in vitro-derived bovine blastocysts.

3) View Attachment 1

4) View Attachment 2: Complex Induction of Bovine Uterine Proteins by Interferon-Tau1

5) http://www.biomedsearch.com/nih/Measurement-interferon-tau-IFN-stimulated/20554404.html

6) http://onlinelibrary.wiley.com/doi/10.1002/mrd.20431/abstract

In vivo expression of interferon tau mRNA by the embryonic trophoblast and uterine concentrations of interferon tau protein during early pregnancy in the cow

7) http://www.reproduction-online.org/cgi/content/abstract/121/1/175 (Free)

Relationship between maternal endocrine environment, early embryo development and inhibition of the luteolytic mechanism in cows

8 ) http://pubget.com/search?q=authors:%22J%20C%20Green%22

As a member of Biology-forums.com, we can purchase this paper for you free of charge.
 Attached file(s) 
(1280.05 KB)
You must login or register to gain access to these attachments.
New Topic      
Explore
Post your homework questions and get free online help from our incredible volunteers
  1021 People Browsing
Gallery
  
 714
  
 140
  
 427
Your Opinion
What's your favorite funny biology word?
Votes: 156