Interferon
tau is the signal from the developing embryo to the mother that she is pregnant. It is secreted by the
trophoblast cells into the uterine lumen in days 13-21 of pregnancy. It decreases endometrial oxytocin receptors, which then cannot stimulate PGF-2-alpha synthesis, preventing luteolysis. It promotes uterine implantation by increasing protein synthesis in glands.
I found the following papers to aid you:1)
http://www.ncbi.nlm.nih.gov/pubmed/20554404 Measurement of interferon-tau (IFN-tau) stimulated gene expression in blood leukocytes for pregnancy diagnosis within 18-20d after insemination in dairy cattle.
2)
http://www.ncbi.nlm.nih.gov/pubmed/11343838Genetic and environmental determinants of interferon-tau secretion by in vivo- and in vitro-derived bovine blastocysts.
3) View Attachment 1
4) View Attachment 2: Complex Induction of Bovine Uterine Proteins by Interferon-Tau1
5)
http://www.biomedsearch.com/nih/Measurement-interferon-tau-IFN-stimulated/20554404.html6)
http://onlinelibrary.wiley.com/doi/10.1002/mrd.20431/abstractIn vivo expression of interferon tau mRNA by the embryonic trophoblast and uterine concentrations of interferon tau protein during early pregnancy in the cow
7)
http://www.reproduction-online.org/cgi/content/abstract/121/1/175 (Free)
Relationship between maternal endocrine environment, early embryo development and inhibition of the luteolytic mechanism in cows
8 )
http://pubget.com/search?q=authors:%22J%20C%20Green%22As a member of Biology-forums.com, we can purchase this paper for you free of charge.