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Use the data to determine the DNA consensus sequence for the 16 nucleotides
fodog414
fodog414
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9 years ago
9 years ago
Use the data to determine the DNA consensus sequence for the 16 nucleotides
The following table lists α-globin and β-globin gene sequences for the 12 nucleotides preceding the start codon and the first nucleotide following the start codon. The data are for 16 vertebrate globin genes reported by Kozak (1987). The sequences are written from -12 to +4 with the start codon sequence in capital letters.
Part A
Use the data to determine the DNA consensus sequence for the 16 nucleotides (-12 to +4) surrounding the start codon in the 16 selected α-globin and β-globin genes. Assume the most prevalent nucleotide at any position is incorporated into the consensus sequence.
Express your answer as a sequence of 16 DNA nucleotides separated by dashes. Example: 5'-A-C-T-G-3'
5'-C-C-A-G-C-T-G-C-A-C-C-G-C-A-T-G-3' not right only one attempt left
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padre
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#1
Staff Member
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9 years ago
5'-C-C-C-G-C-C-G-C-C-A-C-C-A-U-G-G-3'
All you need to do is select the nucleotide in each position that appears the most frequently, and to make sure to include the "A-U-G" start codon sequence at the correct position, between the -1 and +1 nucleotide position. It doesn't appear in this sequence, but if there were any T's present, they would have to be denoted as "U" since you need to write the cognate RNA sequence.
1 Vote
TGTP1021
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Mastering in Nutritional Biology
Tralalalala
fodog414
Author
wrote...
#2
9 years ago
This was wrong
last attempt remaining not sure where?!
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padre
wrote...
#3
Staff Member
Educator
9 years ago
I'm not sure then, sorry
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Mastering in Nutritional Biology
Tralalalala
fodog414
Author
wrote...
#4
9 years ago
It's okay I'll post an answer as soon as i can
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padre
wrote...
#5
Staff Member
Educator
9 years ago
Thanks
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Mastering in Nutritional Biology
Tralalalala
helensx
wrote...
#6
9 years ago
5'-c-c-a-g-c-g-c-c-c-a-c-c-a-u-g-g-3'
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chasewright
wrote...
#7
9 years ago
It says that's incorrect :/
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fodog414
Author
wrote...
#8
9 years ago
5'-C-C-A-G-C-A-G-C-C-A-C-C-A-T-G-G-3'
the correct answer^^^^
3 Votes
padre
,
Zbrutha,
tangoluv713
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padre
wrote...
#9
Staff Member
Educator
9 years ago
Thanks for updating us
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Mastering in Nutritional Biology
Tralalalala
lclever
wrote...
#10
9 years ago
Thanks
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caughtinannette
wrote...
#11
8 years ago
Can anyone actually explain how to do this? I have a similar problem to do so just the answer won't help me.
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