alanine-glucose cycle with that of the Cori cycl

In the glucose-alanine cycle, glucose is degraded into pyruvate through glycolysis. Pyruvate combines with glutamate to produced alanine and alpha ketoglutarate via alanine transaminase:

Glucose [pyruvate] + glutamate alanine + alpha-ketoglutarate

The alanine amino acids that are produced then travel to the liver where they are transaminated and converted into pyruvate. This is done by the reverse reaction shown above; in fact, you will notice that nh4+ isn’t shown in the reaction. This is because glutamate is converted into alpha-ketoglutarate +nh4+ via deamination using the enzyme glutamate dehydrogenase. The pyruvate is converted back into glucose via gluconeogenesis; recall that deamination and the production of urea occurs in the liver:

Alanine + alpha-ketoglutarate glutamate + [pyruvate] glucose

The cori cycle is similar to this process because rather than having pyruvate produce alanine, pyruvate is converted in lactate, especially under anaerobic conditions. The lactate travels to the liver where it is converted back into pyruvate and pyruvate into glucose via gluconeogenesis. The glucose returns back to the muscle where it is used to harvest energy.