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AppleGrabFace AppleGrabFace
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5 years ago
Provide three pieces of evidence to support the dopamine hypothesis of schizophrenia.
 
  What will be an ideal response?
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5 years ago
Drugs that increase extracellular levels of dopamine, e.g., cocaine, amphetamine, PCP, MAOIs can induce schizophrenia-like symptoms or exacerbate those with schizophrenia, whereas drugs that deplete DA levels or competitively block DA receptors or reduce DA release generally reduce the symptoms in schizophrenics. Some schizophrenics have higher density of DA receptors than normal individuals in some areas of the brain.
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