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How do the DNA polymerase repair mechanisms work?

GermanBiter14

wrote...

Posts: 778

Rep:

6 years ago

How do the DNA polymerase repair mechanisms work?

How do the DNA polymerase repair mechanisms work?

What will be an ideal response?

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The T.

wrote...

#1

6 years ago

Both DNA Pol I and DNA Pol III have 3'-to-5' exonuclease activity and can remove nucleotides from the end of a DNA chain as part of an error correction mechanism. If an incorrect base is inserted by DNA polymerase, and the error is recognized immediately, the exonuclease activity excises the erroneous nucleotide from the new strand. After excision, the DNA polymerase resumes motion in the forward direction and inserts the correct nucleotide.

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