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2 weeks ago
An adult patient has developed renal failure secondary to an overdose of a nephrotoxic drug. Which of the following assessment findings would the nurse recognize as being most suggestive of impaired erythropoiesis?
A)Frequent infections and low neutrophil levels
B)Fatigue and increased heart rate
C)Agitation and changes in cognition
D)Increased blood pressure and peripheral edema
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Abrams' Clinical Drug Therapy: Rationales for Nursing Practice
Edition: 10th
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As RBCs decrease, conditions related to inadequate hematopoiesis develop. Clinical manifestations of inadequate erythropoiesis include anemia. This results in a decrease in the oxygen-carrying capacity of blood and consequently a decreased oxygen availability to the tissues. A compensatory increase in heart rate and cardiac output initially increases cardiac output, offsetting the lower oxygen-carrying capacity of the blood.

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