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What cytokine inhibits cytokine production from macrophages to down-regulate the immune response?

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What cytokine inhibits cytokine production from macrophages to down-regulate the immune response?

What cytokine inhibits cytokine production from macrophages to down-regulate the immune response?
A) interleukin-5
B) interleukin-10
C) interferon-γ
D) interleukin-4
E) interferon-α

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