Researchers have discovered a new compound, named 'darwinolide', inside an Antarctic sponge,
Dendrilla membranosa (above, middle), that has shown to kill 98.4 percent of methicillin-resistant
Staphylococcus aureus (MRSA) cells it comes in contact with. Lab tests so far suggest that it has a unique structure that allows it to penetrate the 'biofilm' that MRSA throws up to protect itself from treatments.
The next step is to synthesise darwinolide in the lab, so they don't have to rely on extracting it from live Antarctic sponges. If the researchers are able to show that they can use darwinolide to fight MRSA in a clinical setting, it could save the lives of tens of thousands of people every years.
Source: http://pubs.acs.org/doi/abs/10.1021/acs.orglett.6b00979
