A landmark study, based on genetic analysis of nearly 65,000 people, has revealed that a person's risk of schizophrenia is increased if they inherit specific variants in a gene related to "synaptic pruning" - the elimination of connections between neurons. The findings represent the first time that the origin of this devastating psychiatric disease has been causally linked to specific gene variants and a biological process. They also help explain decades-old observations: synaptic pruning is particularly active during adolescence, which is the typical period of onset for schizophrenia symptoms, and brains of schizophrenic patients tend to show fewer connections between neurons. The gene, called component 4 (C4), plays a well-known role in t ...

At only eights years-old, Zion Harvey is the youngest person with a double hand transplant ever. Four teams of surgeons worked over 11 hours to complete the complicated operation. Zion lost both of his hands and feet when he contracted sepsis at age two and experienced multiple organ failures. When he was four, he received a kidney transplant from his mother, and leg prosthetics have enabled him to engage in many activities.