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Why do hard liquors keep you warm?
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Anyone who has ever taken a shot of hard liquor (tequila, brandy) can tell you: it burns on the way down. But it's not the alcohol itself that's burning your throat. Instead, the ethanol in the liquid is making your throat's VR1 heat receptors (left) more sensitive, prompting them to perceive your own body temperature as hot. Normally, the VR1 receptors activate at 42° Celsius, but alcohol lowers this threshold to around 34° C, which is 4° C less than your bodies regulated temperature. ...
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4324 |
duddy |
8 years ago |
One step closer to invisibility
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Seeing through objects may seem like something straight out of a comic book, but researchers have found a way to make entire animals transparent – from their brains to their bones. The method lets fluorescent proteins visibly shine through bodies, lighting up entire vascular systems (above) and other structures. To produce such light shows, researchers treat euthanized rodents with several organic solvents to remove the water and lipids that made them opaque. The technique is dubbed uDISCO because it’s a variant of the original DISCO technique, which stands for 3D imaging of solvent-cleared organs. This technique allows the highest resolution images yet for a whole body, its creators report online today in Nature Methods, and it can create ...
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3284 |
duddy |
8 years ago |
Here's why your hair will eventually turn gray
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As soon as we're born, we're destined to age. Some of us age gracefully - we enjoy years of youthfulness - while others experience hair loss, wrinkles, and greying earlier than expected. Found in the core of each hair, a pigment known as melanin gives rise to a person's hair color. This universal pigment is also found in our skin and eyes, giving use our unique physical traits. Dark and light versions of melanin - eumelanin and phaeomelanin, respectively - combine in various combinations to create all natural hair colors. Melanin itself is the product of a specialized cell, the melanocyte, which is found in each hair follicle, from which the hair grows. As hair grows, the melanocyte injects melanin into the hair cells, which contain the s ...
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9649 |
duddy |
9 years ago |
First ever image taken of a single protein
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Proteins are subatomic biomolecules. They're produced by cells, so it's logical to assume that they are much tinier than cells, and of course, much tinier than the organelles that produce them. In a remarkable achievement, scientists have now obtained the first-ever photographs of single proteins. Using a "holography electron microscope," researchers tested on a range of protein samples, all just a few nanometers in size. Hemoglobin, the protein that transports oxygen in red blood cells, and cytochrome c, the protein that transfers electrons within the body, were just two examples. Source: arXiv ...
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8593 |
duddy |
9 years ago |
Stay away from the castor bean
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Some organisms, such as the castor bean plant ( Ricinus communis), produce substances that inhibit the synthesis of proteins (called translation) within a cell. (The plant, which is native to Africa, is not related to the species of bean plants with which you are likely more familiar.) A protein called ricin, produced within the castor seeds is an extremely potent inhibitor of protein synthesis. In fact, it is one of the strongest natural toxins produced. A single chewed seed can kill child! If the ricin were purified, it would take an amount equivalent to only a few grains of salt to kill an adult. Ricin kills cells by enzymatically cleaving covalent bonds within the large and small ribosomal subunits, rendering the protein-building factori ...
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20330 |
savio |
9 years ago |
Why do men with dark hair sometimes possess a reddish beard?
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It has to do with a single gene! More than a decade ago, researchers discovered that one gene (MC1R) on chromosome 16 plays an important role in giving people red hair. MC1R task is to make the protein melanocortin 1. This protein plays an important role in converting red pigment into black pigment. If you end up with only one mutated MC1R gene, red hair can appear in unwanted places, like your beard. When someone inherits two mutated versions of the MC1R-gene (one from each parent), less red pigment is converted into black pigment. ...
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14984 |
duddy |
9 years ago |
Spider-man would be proud of this finding
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Researchers have uncovered the mechanism that allows spiders to build such strong webs. According to the study, both ends of the spider's silk grand have different pH levels, which helps these proteins become a solid fibre that can be spun into a solid web. The researchers also found that the pH level has different effects on the stability of the two regions at each end of the spidroin proteins. “While one of the ends tended to pair up with other molecules at the beginning of the duct (N-terminal) and became increasingly stable as the acidity increased along the duct, the other end (C-terminal) destabilised as the acidity increased, and gradually unfolded until it formed the structure characteristic of silk at the acidic pH of 5.5”, ex ...
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5275 |
duddy |
10 years ago |
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