At only eights years-old, Zion Harvey is the youngest person with a double hand transplant ever. Four teams of surgeons worked over 11 hours to complete the complicated operation. Zion lost both of his hands and feet when he contracted sepsis at age two and experienced multiple organ failures. When he was four, he received a kidney transplant from his mother, and leg prosthetics have enabled him to engage in many activities.

Isn't it strange, two FDA-approved drugs - topical ruxolitinib or tofacitinib - can reawaken dormant hair follicles! According to the study, within 3 weeks, mice that received topical ruxolitinib or tofacitinib had regrown nearly all their hair (right photo; drug was applied only to the right side of the mouse). Little to no hair growth occurred in control mice during the same timeframe (left photo). According to researchers at Columbia University Medical Center, inhibiting a family of enzymes inside hair follicles that are suspended in a resting state restores hair growth.

These drugs, known as JAK inhibitors have been approved to treat blood diseases (ruxolitinib) and the other for rheumatoid arthritis (tofacitinib). Both are being tested ...

According to a new study published in Cell Metabolism, mice who spent their free time on a running wheel were better able to shrink tumors (a 50 percent reduction in tumor size) compared to their less active counterparts. Researchers found that the surge of adrenaline ( epinephrine) that comes with a high-intensity workout helped to move cancer-killing immune (NK) cells toward lung, liver, or skin tumors implanted into the mice.

While the research is hopeful for patients looking for inexpensive ways to manage their cancer, more needs to be learned about the effects of exercise on metastasis and longevity, as well as if the observations hold true in humans. Scientists also wants to explore the combined impact of anti-cancer treatments and ex ...

Stan Larkin (pictured on the right), who's now 25, was diagnosed with familial cardiomyopathy. This form of disease results in the heart having difficulty pumping enough blood through the body. Faced with a lack of compatible heart donors, Stan underwent an operation in 2014 to remove his failing heart and replace it with an external total artificial heart, dubbed the Freedom portable driver.

This battery-powered device uses compressed air to pump blood around the body in the same way a heart does, and as the name suggests, it is portable and only weighs 6 kilograms (13 pounds). The device does an incredible job at keeping the patient in a healthy condition while a donor heart becomes available, but it isn’t considered a long-term option. ...

Down syndrome  is caused by a triple copy of chromosome 21, which leads to a number of cognitive and physical delays. Now researchers from the Sanford-Burnham Medical Research Institute in La Jolla, California, have found a protein that restores the some of the cognitive and behavioral disorders found in the disease.

Mice who were deficient in the SNX27 protein exhibited similar characteristics to mice with Down syndrome—namely, they had fewer glutamate receptors, which are important for learning and memory, the team reported in Nature Medicine on Sunday (March 24). The researchers also showed that in mice with Down syndrome, the protein is blocked by a molecule encoded on chromosome 21, and produced in excess in Down syndrome mice as a re ...

Asthma is one of those illnesses that is so common that we never stop to question what causes it and how it could be treated. Affecting more than 25 million people, asthma is one of the most common chronic respiratory conditions in the United States. It is caused by the increased reactivity of the tracheobronchial tree to various stimuli, including exercise, allergies, or infections of the respiratory tract. Symptoms include, but are not limited to breathlessness, cough, wheezing, and chest tightness.


The most commonly used medications for asthma are: bronchodilators, xanthine derivatives, leukotriene inhibitors, corticosteroids, and mast cell stabilizers (see full list below). Xanthine derivatives treat asthma by re ...

For quite some time it's been known in the medical community that a link exists between depression and heart disease. For example, large epidemiological surveys typically find that 1.5 to 3 percent of the population is depressed at any given time. Among patients with heart disease, however, the rate of depression is closer to 18 percent. Similarly, about 1 in 6 people in the general population has an episode of major depression during their lifetimes, compared to about 50 percent of people with heart disease. Finally, a Canadian study revealed that of 222 patients who had suffered heart attacks, those who were depressed were four times as likely to die within the next 6 months.

Amassing this evidence is one thing, but explaining it is quite ...