Having more cells usually puts one at a higher risk for cancer - but not for the elephant. Despite packing 100 times as many cells as humans, this towering animal can keep cancer at bay thanks to extra copies of a tumor-fighting gene. Researchers found that Asian elephants harbor 30 to 40 copies of the gene that encodes the protein p53, one of the most important mechanisms for preventing cancer and maintaining cell division. If cells have DNA damage that could spawn tumors, p53 prevents them from dividing until they make repairs or spurs them to commit suicide. In contrast, humans sport only two copies of the gene for p53, and so does elephants’ closest living relative, the rock hyrax. The extra copies probably accumulated millions of yea ...

The microbes that live in your body outnumber your cells 10 to one. Recent studies suggest these tiny organisms help us digest food and maintain our immune system. Now, researchers have discovered yet another way microbes keep us healthy: They are needed for closing the blood-brain barrier, a molecular fence that shuts out pathogens and molecules that could harm the brain.

If you’re not already acquainted, meet Mycobacterium tuberculosis – a wildly successful bacterium that has marched in lockstep with our population growth and history. The cause of tuberculosis, this bacterium is said to infect a new host every single second.

Research lead Caitlin Pepperell from University of Wisconsin-Madison remarked, "Evolutionary theory predicts that M. tuberculosis populations should be vulnerable to extinction. Yet it is obviously highly prevalent. It must have some incredibly clever strategies and tricks to hang on."

A paper published last month in PLoS Pathogens investigated 63 genomes from the bacteria and related pathogenic mycobacteria to gain insight into how natural election pressures have shaped its evolution and ...

CellCraft is a truly great flash game about building, controlling, and surviving as a human cell, viewed at the microscopic scale. I was surprised to find how accurate the game was, depicting organelles correctly and even conversion ratios of glucose to ATP. The game is a great primer for those who wish to learn some cell biology, or even for those of us who know plenty about the cell but want a refresher without cracking open a textbook.