An injectable drug, called ATX-101, currently being tested melts away "submental fat", better known as the double chin. According to its makers, ATX-101 can be injected in a clinic and takes just five minutes. It consists of deoxycholic acid, a naturally-occurring molecule that helps us break down fat, which effectively destroys the membranes of fat cells, causing them to burst and then be metabolised by the body. ...

Isn't it strange, two FDA-approved drugs - topical ruxolitinib or tofacitinib - can reawaken dormant hair follicles! According to the study, within 3 weeks, mice that received topical ruxolitinib or tofacitinib had regrown nearly all their hair (right photo; drug was applied only to the right side of the mouse). Little to no hair growth occurred in control mice during the same timeframe (left photo). According to researchers at Columbia University Medical Center, inhibiting a family of enzymes inside hair follicles that are suspended in a resting state restores hair growth.

These drugs, known as JAK inhibitors have been approved to treat blood diseases (ruxolitinib) and the other for rheumatoid arthritis (tofacitinib). Both are being tested ...

A simplified illustration of the various brain functions...

The importance of adequate, non-distracted, deep sleep could not be emphasized enough. Recent research has put the brain yet again under the spotlight, this time only to shed some light on one more reason we should be getting our sleep and why. Make sure to watch the video above. It is hands down, one of the best TED talks I have listened to. As for now, I'mma go make my CSF flush my amyloid betas Nighty, night!

Good news for pain-pill poppers: Ibuprofen (found in Advil) may help you live longer. A new study shows that it increases life span in lab organisms, raising the possibility it does the same thing in people.

To put ibuprofen through its paces, biochemist Michael Polymenis of Texas A&M University, College Station, and colleagues gave yeast, nematode worms, and fruit flies doses of the drug that are comparable to what humans would take. The life spans of all three types of organisms increased if they received ibuprofen, the researchers report today in PLOS Genetics. In yeast, for instance, ibuprofen stretched life span by 17%, half of what researchers can produce by cutting the cells’ food supply (another approach to increasing longevity). ...

A doctor chronicles the signatures of his patient as the disease took hold of her. Our love goes out to anyone who's dealt with this awful disease in some way.

A possible vaccine for lung cancer! In a country known for cigars, lung cancer is one of the major killers in Cuba. So for the past 25 years, they’ve been developing Cimamax, which is now available freely to Cubans. According to a Phase II trial conducted in Cuba in 2008, lung cancer patients who received the vaccine lived an average of four to six months longer than those who didn’t. This led Japan and some European countries to trial the drug as well.

The drug itself is far from flawless and, by attacking a cell’s protein rather than the tumour directly, can have severe side effects, including – of all things - causing a higher risk of cancer. It might not be a "cure" in the traditional sense, but it's a way of managing the disease. What t ...

A panel of respected physicians has written a major paper advising the public against 'wasting money' on multivitamins. Their report analysed 27 clinical studies: "We believe that the case is closed — supplementing the diet of well-nourished adults with (most) mineral or vitamin supplements has no clear benefit and might even be harmful. These vitamins should not be used for chronic disease prevention. Enough is enough."

Source:

https://annals.org/aim/fullarticle/1789253/enough-enough-stop-wasting-money-vitamin-mineral-supplements ...